Grupo de BIOFISICA DE VIRUS

 

GNAInvestigador responsable:

 
Dr. Mariano Dellarole
T: +54 11 4899-5500 int 6506
E: mdellarole@cibion.conicet.gov.ar

 

 

 

ACTIVIDADES

Investigamos virus responsables de causar enfermedades infecciosas locales, emergentes y re-emergentes. Nuestras preguntas buscan comprender mecanismos moleculares que tengan potencial para su aplicación como tratamiento o detección. Utilizamos y desarrollamos herramientas de trabajo de la rama de la biofísica y bioquímica de proteínas.

METODOS

Bioquímica y biofísica de proteínas

PUBLICACIONES SELECCIONADAS   -   >Lista completa de publicaciones

“Glycan-Glycan Interaction Determines Tropism toward Human T Lymphocytes”
Belotserkovsky I, Brunner K, Pinaud L, Rouvinski A, Dellarole M, Baron B, Dubey G, Samassa F, Parsot C, Sansonetti P, Phalipon A. MBio 2018

 

“The bright and the dark side of human antibody responses to flaviviruses:lessons for vaccine design”
Rey FA, Stiasny K, Vaney MC, Dellarole M, Heinz FX. EMBO Rep.2017 

 

“High-Resolution Mapping of a Repeat Protein Folding Free Energy”
Fossat MJ, Dao TP, Jenkins K, Dellarole M, Yang Y, McCallum SA, Garcia AE, Barrick D, Roumestand C, Royer CA Biophys. J.2016 Dec; 111 (11) 2368-2376

 

“Unusual Reversible Oligomerization of Unfolded Dengue Envelope Protein Domain 3 at High Temperatures and Its Abolition By a Point Mutation"
Saotome T, Nakamura S, Islam MM, Nakasawa A, Dellarole M, Arisaka F, Kidokoro S, Kuroda Y Biochemistry 2016 Aug; 55(32) 4469-75

 

“Evolutionarily Conserved Pattern of Interactions in a Protein Revealed by Local Thermal Expansion Properties"
Dellarole M, Caro JA, Roche J, Fossat M, Barthe P, García Moreno E B, Royer CA, Roumestand C J.Am.Chem.Soc.2015 Jul ;137 (29);9354-62

 

“Exploring the Protein Folding Pathway with High-Pressure NMR:Steady-State and Kinetics Studies”
Roche J, Dellarole M, Royer CA, Roumestand C. Subcell.Biochem (2015)  72:261-78

 

“Molecular basis for bacterial peptidoglycan recognition by LysM domains,”
Mesnage S, Dellarole M, Baxter NJ, Rouget JB, Dimitrov JD, Wang N, Fujimoto Y, Hounslow AM, Lacroix-Desmazes S, Fukase K, Foster SJ, Williamson MP. Nat Commun 2014 ;5:4269

 

“Measuring residual dipolar couplings at high hydrostatic pressure: robustness of alignment media to high pressure”
Sibille N, Dellarole M, Royer C, Roumestand C. J.Biomol.NMR 2014 Jan; 58 (1) 9-16

 

“High-pressure fluorescence applications,"
Dellarole M, Royer CA. Methods Mol. Biol.; (2014); 1076:53-74

 

“Low-cost equilibrium unfolding of heme proteins using 2 μl samples"
Guca E, Roumestand C, Vallone B, Royer CA, Dellarole M. Anal. Biochem. 2013. Dec; 443; (1) 13-5