Espectrometría de Masas Bioanalítica: publicaciones de la  Dra. María Eugenia Monge

  • Muñoz‑Bernart, M., Budnick, N., Castro, A.,  Manzi, M., Monge, M. E.,  Pioli, J.,  Defranchi, S., Parrilla, G.,  Santilli, J. P., Davies, K., Espinosa, J. M., Kobayashi, K., Vigliano, C., Perez‑Castro C.  “S‑adenosylhomocysteine hydrolase‑like protein 1 (AHCYL1) inhibits lung cancer tumorigenesis by regulating cell plasticity.” Biology Direct (2023) 18:8. Leer publicación


  • M. Manzi, N. Zabalegui y María Eugenia Monge. Postoperative Metabolic Phenoreversion in Clear Cell Renal Cell Carcinoma. J. Proteome Res. American Chemical Society (2023), Leer publicacion


  • Monge M.E., Martinefski M.R., Bollini M., Pontel L.B.. UHPLC-HRMS-Based Analysis of S-Hydroxymethyl-Glutathione, GSH, and GSSG in Human Cells. Methods in Molecular Biology, 2675, pp. 117 - 132 (2023). DOI: 10.1007/978-1-0716-3247-5_10. Leer publicación


  • Corey D. Broeckling, Richard D. Beger, Leo L. Cheng, Raquel Cumeras, Daniel J. Cuthbertson, Surendra Dasari, W. Clay Davis, Warwick B. Dunn, Anne Marie Evans, Alvaro Fernández-Ochoa, Helen Gika, Royston Goodacre, Kelli D. Goodman, Goncalo J. Gouveia, Ping-Ching Hsu, Jennifer A. Kirwan, Dritan Kodra, Julia Kuligowski, Renny Shang-Lun Lan, María Eugenia Monge, Laura W. Moussa, Sindhu G. Nair, Nichole Reisdorph, Stacy D. Sherrod, Candice Ulmer Holland, Dajana Vuckovic, Li-Rong Yu, Bo Zhang, Georgios Theodoridis, and Jonathan D. Mosley. Current Practices in LC-MS Untargeted Metabolomics: A Scoping Review on the Use of Pooled Quality Control Samples. Analytical Chemistry Article ASAP DOI: 10.1021/acs.analchem.3c02924. Leer publicación


  •  T. Schmidt De León, M. L. Salum, Y. Matsushita, K. Fukushima, M. E. Monge,* and R. Erra-Balsells*, “ESI-MS reveals preferential complex formation of carbohydrates with Z sinapinic acid compared with the E-isomer” New Journal of Chemistry 46 (2022) 18563. DOI: 10.1039/D2NJ02789E. (*autor correspondiente)

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  • C. Umansky, A. E. Morellato, M. Rieckher, M. A. Scheidegger, M. R. Martinefski, G. A. Fernández, O. Pak, K. Kolesnikova, H. Reingruber, M. Bollini, G. P. Crossan, N. Sommer, M. E. Monge, B. Schumacher and L. B. Pontel, 
    “Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity” 
    Nature Communications (2022) 13:745. Ver publicación


  • S. Tomaz, D. Wang, N. Zabalegui, D. Li, H. Lamkaddam, F. Bachmeier, A. Vogel, M. E. Monge, S. Perrier1, U. Baltensperger, C. George, M. Rissanen, M. Ehn, I. El Haddad, M. Riva,
    “Structures and reactivity of peroxy radicals and dimeric products revealed by online tandem mass spectrometry”
    Nature Communications (2021) 12:300. Ver publicación


  • Malena Manzi, Martín Palazzo, María Elena Knott, Pierre Beauseroy, Patricio Yankilevich, María Isabel Giménez, and María Eugenia Monge
    "Coupled Mass-Spectrometry-Based Lipidomics Machine Learning Approach for Early Detection of Clear Cell Renal Cell Carcinoma"
    Journal of Proteome Research  (2021) 20 (1): 841-857. Ver publicación


  • M.R. Martinefski, B. Elguero, M. E. Knott, D. Gonilski, L. Tedesco, J. M. Gurevich Messina, C. Pollak, E. Arzt, and M. E. Monge*
    “Mass Spectrometry-based Metabolic Fingerprinting Contributes to Unveil the Role of RSUME in Renal Cell Carcinoma Cell Metabolism”
    Journal of Proteome Research (2021) 20 (1) 786-803.  Ver publicación


  • G. Riquelme,  N. Zabalegui, P. Marchi, C. M. Jones y  M. E. Monge*
    “A Python-Based Pipeline for Preprocessing LC-MS Data for Untargeted Metabolomics Workflows”
    Metabolites 10 (2020) 416. Ver publicación


  • A. M.  Evans, C. O’Donovan, M. Playdon, C. Beecher, R. D. Beger, J. A. Bowden, D. Broadhurs, C. B. Clish , S. Dasari, W.B. Dunn, J. L. Griffin, T. Hartung, P.‑ C. Hsu, T. Huan, J. Jans,  C. M. Jones, M. Kachman, A. Kleensang, M. R. Lewis, M. E. Monge, J. D. Mosley, E. Taylor, F. Tayyari, G. Theodoridis, F. Torta, B.K. Ubhi,  D. Vuckovic,   behalf of the Metabolomics Quality Assurance, Quality Control Consortium (mQACC),
    "Dissemination and análisis of the quality assurance (QA) and quality control (QC) practices of LC-MS based untargeted metabolomics practitioners.”
    Metabolomics 16 ( 2020); 113. Ver publicación


  • N. Zabalegui, M. Manzi, A. Depoorter, N. Hayeck, M. Roveretto, C. Li, M. van Pinxteren, H. Herrmann, C. George, and M. E. Monge *,
    “Seawater Analysis by Ambient Mass Spectrometry-Based Seaomics”
    Atmospheric Chemistry and Physics 20(2020) 6243–6257. Ver publicación


  • M. van Pinxteren, K. Wadinga Fomba, N. Triesch, C. Stolle, O. Wurl, E. Bahlmann, X. Gong, J. Voigtländer, H. Wex, T.-B. Robinson, S. Barthel, S. Zeppenfeld, E. H. Hoffmann, M. Roveretto, C. Li, B. Grosselin, V. Daële, F. Senf, D. van Pinxteren, M. Manzi, N. Zabalegui, S. Frka, B. Gašparović, R. Pereira, T. Li, L. Wen, J. Li, C. Zhu, H. Chen, J. Chen, B. Fiedler, W. von Tümpling, K. A. Read, S. Punjabi, A. C. C. Lewis, J. R. Hopkins, L. J. Carpenter, I. Peeken, T. Rixen, D. Schulz-Bull, M. E. Monge, A. Mellouki, C. George, F. Stratmann, and H. Herrmann,
    “Marine organic matter in the remote environment of the Cape Verde Islands – An introduction and overview to the MarParCloud campaign”
    Atmospheric Chemistry and Physics 20(2020) 6921–6951. Ver publicación


  • A. Seleem, N. Rodrigues de Almeida, Y. Singh Chhonker, D. J. Murry, Z. da Rosa Guterres, A. M. Blocker, S. Kuwabara, D. J. Fisher, E. S. Leal, M. R. Martinefski, M. Bollini, M. E. Monge, S. P. Ouellette, M. Conda-Sheridan,
    “Synthesis and Antichlamydial Activity of Molecules Based on Dysregulators of Cylindrical Proteases”
    Journal of Medicinal Chemistry (2020) 63 (2020) 4370-4387. Ver publicación


  • Manzi, G. Riquelme, N. Zabalegui and M. E. Monge*,
    “Improving Diagnosis of Genitourinary Cancers: Biomarker Discovery Strategies through Mass Spectrometry-based Metabolomics” 
    Journal of Pharmaceutical and Biomedical Analysis 178(2020) 112905. Ver publicación


  • Xiaoling Zang, Maria Eugenia Monge, David A. Gaul, Nael A. McCarty, Arlene Stecenko, Facundo M Fernandez
    “Early Detection of Cystic Fibrosis Acute Pulmonary Exacerbations by Exhaled Breath Condensate Metabolomics”
    Journal of Proteome Research 19 (2020) 144-152. Ver publicación


  • Emilse Leal, Natalia Adler, Gabriela Fernández, Leopoldo Gebhard, Leandro Battini, Maria Aucar, Mariela Videla, María Eugenia Monge, Alejandro Hernández de los Ríos, John Acosta Dávila, María Morell, Sandra Cordo, Cybele García, Andrea Gamarnik, Claudio Cavasotto, Mariela, Bollini
    "De novo design approaches targeting an envelope protein pocket to identify small molecules against dengue virus"
    European Journal of Medicinal Chemistry 182 (2019) article 111628. Ver publicación


  • X. Zang, M. E. Monge*, F.M. Fernández*
    “Mass Spectrometry-Based Non-targeted Metabolic Profiling for Disease Detection: Recent Developments”
    Trends in Analytical Chemistry 118 (2019) 158-169. Ver publicación


  • M. E. Monge, J. N. Dodds, E. S. Baker, A. S. Edison, F. M. Fernández
    “Challenges in Identifying the Dark Molecules of Life”
    Annual Review of Analytical Chemistry 12 (2019) 177-199. Ver publicación


  • Chaevien S. Clendinen, David A. Gaul, Maria Eugenia Monge, Rebecca S Arnold, Arthur S Edison, John A Petros, and Facundo M Fernandez
    "Preoperative Metabolic Signatures of Prostate Cancer Recurrence Following Radical Prostatectomy"
    Journal of Proteome Research 18 (2019) 1316–1327. Ver publicación


  • X. Zang, M. E. Monge, D. A. Gaul, and F. M. Fernández
    "Flow Injection-Traveling Wave Ion Mobility-Mass Spectrometry for Rapid Prostate Cancer Metabolomics"
    Analytical Chemistry 90 (2018) 13767-13774. Ver publicación


  • María Elena Knott, Malena Manzi, Nicolás Zabalegui, Mario O. Salazar, Lydia I. Puricelli, and María Eugenia Monge*
    “Metabolic Footprinting of a Clear Cell Renal Cell Carcinoma in vitro Model for Human Kidney Cancer Detection”
    Journal of Proteome Research 17 (2018) 3877–3888. Ver publicación


  • Daniela M. Fidalgo, Maria Eugenia Monge, Oscar Varela, Adriana Kolender
    "Synthesis, Secondary Structure and Anion Binding of Acyclic Carbohydrate‐derived Oligo(amide‐triazole)s"
    European Journal of Organic Chemistry 2018 (2018) 6787–6799. Ver publicación


  • C. S. Clendinen, M. E. Monge*, F. M. Fernandez*
    "Ambient Mass Spectrometry in Metabolomics"
    Analyst 142 (2017) 3101-3117. Ver publicación


  • X. Zang, J. J. Pérez, C. M. Jones, M. E. Monge, N. A. McCarty, A. A. Stecenko, F. M. Fernández
    "Comparison of Ambient and Atmospheric Pressure Ion Sources for Cystic Fibrosis Exhaled Breath Condensate Ion Mobility-Mass Spectrometry Metabolomics"
    Journal of The American Society for Mass Spectrometry 28 (2017) 1489-1496. Ver publicación


  • X. Zang, M. E. Monge, N. A. McCarty, A. A. Stecenko, F. M. Fernández
    “Feasibility of Early Detection of Cystic Fibrosis Acute Pulmonary Exacerbations by Exhaled Breath Condensate Metabolomics: A Pilot Study”
    Journal of Proteome Research 16 (2016) 550-558. Ver publicación


  • C. Jones, M. E. Monge, J. Kim, M. M. Matzuk, F. M. Fernández.
    “Metabolomic Serum Profiling Detects Early-Stage High-Grade Serous Ovarian Cancer in a Mouse Model”
    Journal of Proteome Research 14 (2015) 917-927. Ver publicación


  • P. N. Newton, P. Tabernero, P. Dwivedi, M. J. Culzoni, M. E. Monge, I. Swamidoss, D. Mildenhall, M. D. Green, R. Jähnke, M. dos Santos de Oliveira, J. Simao, N. J White, F. M. Fernández
    “Falsified medicines in Africa and public health – ‘No Action–Talk Only’”
    The Lancet Global Health 2 (2014) e509-e510. Ver publicación


  • A. Kaylor, P. Dwivedi, J. J. Pittman, M. E. Monge, G. Cheng, S. Li, F. M. Fernández
    “Plasma-Spray Ionization (PLASI): A Multimodal Atmospheric Pressure Ion Source for Liquid Stream Analysis”
    Journal of The American Society for Mass Spectrometry 25 (2014) 1788-1793. Ver publicación


  • X. Zang, C. M. Jones, T. Q. Long, M. E. Monge, M. Zhou, L. D. Walker, R. Mezencev, A. Gray, J. F. McDonald, and F. M. Fernández
    “Feasibility of Detecting Prostate Cancer by Ultraperformance Liquid Chromatography−Mass Spectrometry Serum Metabolomics”
    Journal of Proteome Research 13 (2014) 3444-3454. Ver publicación


  • M. E. Monge, P. Dwivedi, M. Zhou, M. Payne, C. Harris, B. House, y. Juggins, P. Cizmarik, P. N. Newton, F. M. Fernández, D. Jenkins.
    “A tiered analytical approach for investigating poor quality emergency contraceptives.”
    PLoS ONE 9 (4) (2014) e95353. Ver publicación


  • R. V. Bennett, E. M. Morzan, J. O. Huckaby, M. E. Monge, H. I. Christensen, F. M. Fernández
    “Robotic Plasma Probe Ionization Mass Spectrometry (RoPPI-MS) of Non-PlanarSurfaces”
    Analyst 139 (2014) 2658-2662. Ver publicación


  • M. E. Monge, J. J. Pérez, P. Dwivedi, M. Zhou, N. A. McCarty, A. A. Stecenko, F. M. Fernández
    “Ion Mobility and Liquid Chromatography-Mass Spectrometry Strategies for Exhaled Breath Condensate Glucose Quantitation in Cystic Fibrosis Studies”
    Rapid Communications in Mass Spectrometry 27 (2013) 2263-2271. Ver publicación


  • M. E. Monge, G.A. Harris, P. Dwivedi, F. M. Fernández.
    “Mass Spectrometry-Recent Advances in Direct Open Air Surface Sampling/Ionization”
    Chemical Reviews 113 (2013) 2269-2308. Ver publicación


  • M. E. Monge, T. Rosenørn, O. Favez, M. Müller, G. Adler, A. A.Riziq, Y. Rudich, C. George, B. D’Anna.
    “Alternative pathway for atmospheric particles growth”
    Proceedings of the National Academy of Sciences 109 (2012) 6840-6844 Artículo destacado en PNAS. Ver publicación


  • M. Amenta, M. E. Monge, L. Lizarraga, D. Giacomazza, V. Guarrasi, P. L. San Biagio, D. Bulone.
    “Multivariate Data Analysis of Thermally Treated Sicilian Extravirgin Olive Oils. Coupling of Electronic Nose, Gas Chromatography-mass Spectrometry and Rheology Techniques”
    The Open Food Science Journal 6 (2012) 24-32. Ver publicación


  • V. Zelenay, M. E. Monge, B. D'Anna, C. George, S.A. Styler, T. Huthwelker, M. Ammann.
    “Increased steady state uptake of ozone on soot due to UV/Vis radiation”
    Journal of Geophysical Research – Atmospheres 116 (2011) D11301. Ver publicación


  • C. Baduel, M.E. Monge, D. Voisin, J.L. Jaffrezo, C. George, I. El Haddad, N. Marchand, B. D'Anna.
    “Oxidation of Atmospheric Humic Like Substances by Ozone: A Kinetic and Structural Analysis Approach”
    Environmental Science & Technology 45 (2011) 5238-5244. Ver publicación


  • R. Ammar, M.E. Monge, C. George, B. D’Anna.
    “Photoenhanced NO2 loss on simulated urban grime”
    ChemPhysChem 11 (2010) 3956-3961. Ver publicación


  • M.E. Monge, C. George, B. D'Anna, J.F. Doussin, A. Jammoul, J. Wang, G. Eyglunent, G. Solignac, V. Daele, A. Mellouki.
    “Ozone Formation from Illuminated Titanium Dioxide Surfaces”
    Journal of the American Chemical Society 132 (2010) 8234-8235. Ver publicación


  • M.E. Monge, B. D'Anna and C. George.
    “Nitrogen dioxide removal and nitrous acid formation on titanium oxide surfaces—an air quality remediation process?”
    Physical Chemistry Chemical Physics 12 (2010) 8991-8998. Ver publicación


  • M.E. Monge, B. D’Anna, L. Mazri, A. Giroir-Fendler, M. Ammann, D.J. Donaldson, and C. George
    “Light changes the atmospheric reactivity of soot”
    Proceedings of the National Academy of Sciences 107 (2010) 6605-6609. Ver publicación


  • S.D. Rodriguez, M.E. Monge, A.C. Olivieri, R.M. Negri and D.L. Bernik
    “Time dependence of the aroma pattern emitted by an encapsulated essence studied by means of electronic noses and chemometric analysis”
    Food Research International 43 (2010) 797-804. Ver publicación


  • M.E. Monge, R.M. Negri, D. Giacomazza and D. Bulone
    “Correlation between Rheological properties and limonene release in pectin gels using an electronic nose”
    Food Hydrocolloids 22 (2008) 916-924. Ver publicación


  • M.E. Monge, R.M. Negri, A.A. Kolenderand R. Erra-Balsells.
    “Structural characterization of native high-methoxylated pectin using NMR spectroscopy and UV-Maldi-TOF mass spectrometry. Comparative use of 2,5-dihydroxybenzoic acid and nor-harmane as UV-Maldi matrices”
    Rapid Communications in Mass Spectrometry 21 (2007) 2638-2646. Ver publicación


  • L.J. Nagels, J. Everaert, B. Vissers, J. Sekula, H. Bohets, M. Monge, K. Peeters, N. Vervoort, K. Sadowska, D. Koziowska, M. Brewster, K. Vanhoutte.
    “Molecular interaction sensors: A new type of detector for separation methods”
    LC-GC Europe 20 (2007) 558-566. Ver publicación


  • D. L. Bernik, D. Zubiri, M.E. Monge and R.M. Negri.
    “New kinetic model of drug release from swollen gels under non-sink conditions.”
    Colloids and Surfaces A: Physicochemical and Engineering Aspects 273 (2006) 165-173. Ver publicación


  • M. E. Monge, D. Bulone, D. Giacomazza, R.M. Negri and D.L. Bernik.
    “Electronic Nose screening of limonene release from multicomponent essential oils encapsulated in pectin gels.”
    Combinatorial Chemistry & High Throughput Screening 7 (2004) 337-344. Ver publicación


  • M.E. Monge, D. Bulone, D. Giacomazza, D.L. Bernik and R. Martín Negri.
    “Detection of Flavor Release from Pectin Gels using Electronic Noses.”
    Sensors & Actuators B 101 (2004) 28-38. Ver publicación


  • G. Bazylak, L.J. Nagels, M.E. Monge.
    “Macrocycle versus podant-type neutral ionophore in potentiometric detection of mucolytic agents following separation by various HPLC modes.”
    Chromatographia 57 (2003) 757-765. Ver publicación


  • M.E. Monge, S.M. Bonesi and R. Erra-Balsells.
    “Synthesis and isolation of iodocarbazoles. Direct iodination reaction of N-substituted carbazoles.”
    Journal of Heterocyclic Chemistry 39 (2002) 933-941. Ver publicación


Proceedings o trabajos completos presentados en conferencias

  • M.E. Monge, B. D’Anna, C. George.
    “Photoenhanced uptake of NO2 on soot.”Geochimica et Cosmochimica Acta 19th Annual VM Goldschmidt Conference, Davos, Suiza, 21-26 de junio de 2009. Ver publicación



Capítulos de libros

  • María Eugenia Monge and Facundo M. Fernández
    "An Introduction to Ambient Ionization Mass Spectrometry"
    En Ambient Ionization Mass Spectrometry. Editors: Marek A. Domin and Robert B. Cody, The Royal Society of Chemistry, RSC Publishing, Cambridge, 2014. ISBN: 978-1-84973-926-9. Ver publicación


  • Christina Jones, María Eugenia Monge, Facundo M. Fernández.
    "Metabolite Profiling by Direct Analysis in Real Time Mass Spectrometry"
    En Mass Spectrometry Methods in Metabolomics: Methods and Protocols Series Methods in Molecular Biology, Vol.1198, Editor: Daniel Raftery, Humana Press USA, Springer publishing group, NY, 2014. ISBN 978-1-4939-1258-2. Ver publicación



  • “Mass Spectrometry metabolic profiles as a diagnostic for prostate cancer”, provisional patent submitted 05/23/2014. GTRC ID 6138. USPTO serial number 62/002,728. Inventors: Facundo M. Fernández, John McDonald, Alex Gray, Christina Jones, Xiaoling Zang, María Eugenia Monge (contribución: 20%).