Bioanalytical Mass Spectrometry Group    ->   María Eugenia Monge, Ph.D.

Dra. Monge

Centro de Investigaciones en Bionanociencias
Godoy Cruz 2390, C1425FQD Buenos Aires, Argentina
+54 11 4899-5500 ext 5614
maria.monge@cibion.conicet.gov.ar

Full list of publications

 

 

AREAS OF INTEREST 

  • Analytical Chemistry
  • Analytical Mass Spectrometry (MS)
  • Metabolomics
  • Biomarker discovery for early disease diagnosis
  • Development of MS-based analytical methods
  • Ambient mass spectrometry
  • Atmospheric Chemistry
  • Pharmaceutical Chemistry
  • Tissue analysis

METHODS

  • Mass Spectrometry
  • Liquid Chromatography
  • Multivariate Statistical Analysis (Chemometrics/Bioinformatics)

INSTRUMENTATION

  • Ultra Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS): Waters ACQUITY UPLC I-Class system coupled to a Xevo G2-S QTof mass spectrometer (Waters Corp., Manchester, UK).
  • High Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS): Waters ALLIANCE e2695 Separations Module coupled to 2998 Photodiode Array Detector and Waters SQ Detector 2, a bench-top quadrupole API mass spectrometer (Waters Corp., Manchester, UK).

CURRENT POSITION

  • Independent  Researcher of CONICET

 
RESEARCH EXPERIENCE

  • 11/2019 - present: Research staff (Independent Researcher) of CONICET (National Research Council of Argentina). Principal Investigator at CIBION (Center for Bionanoscience Research). Research Field: Mass spectrometry techniques applied for biomarker discovery and early disease detection, with special emphasis on untargeted metabolomics-based diagnostics. Identification and quantitation of analytes in complex samples.
  • 2015-present: Scientific Officer of the Mass Spectrometry Facility at CIBION. The Mass Spectrometry laboratory is equipped with a UPLC Acquity I-class system coupled to a Xevo G2S Q-TOF mass spectrometer (Waters Corp.) and an Alliance HPLC system coupled to a PDA detector and a single quadrupole SQD2 mass spectrometer (Waters Corp.) and provides services to the Argentine Industry and the Scientific Community.
  • 08/2014-10/2019: Research staff (Associate Investigator) of CONICET (National Research Council of Argentina). Principal Investigator at CIBION (Center for Bionanoscience Research).
  • 06/2019-07/2019: Visiting Researcher at the research group of Dr. Christian George at IRCELYON-CNRS, France. Mass spectrometry-based marine metabolomics.
  • 01/2014-07/2014: Postdoctoral fellowship of CONICET at CIBION. Mass spectrometry techniques applied for biomarker discovery and early disease detection, with special emphasis on untargeted metabolomics-based diagnostics. Identification and quantitation of analytes in complex samples. Advisor: Prof. Pedro F. Aramendía.
  • 02/2012-01/2014: Research Scientist I at Georgia Institute of Technology, Atlanta, USA. Research field: mass spectrometry with a strong focus on metabolomics, quantitative method development for biological samples, complex sample analysis, and pharmaceutical analysis. Advisor: Prof. Facundo M. Fernández
  • 09/2008 –12/2011: Post-doctoral fellow at IRCELYON (Centre National de la Recherche Scientifique) in Lyon, France. Research field: Effect of light on heterogeneous reactions between atmospheric trace gases and different substrates and photoinduced transformations of atmospheric aerosol particles. Advisor: Dr. Christian George.
  • 2008: Postdoctoral Fellow of CONICET. Research field: “Development of potentiometric sensors for detection of pollutants in water combining electronic noses and electronic tongue”. Advisors: Dr. Martín Negri and Dr. Estela Andrade. Place of work: INQUIMAE, Argentina.
  • 2007: Three months stance as a visiting researcher at the Biophysical Institute of Palermo, Consiglio Nazionale delle Ricerche (CNR), Italy to work in the European project: “Realizzazione di un Centro regionale per il Controllo de Qualità di Oli Vergini d’Oliva” Advisor: Dr. Pier Luigi San Biagio.
  • 2006: Two months staying at the University of Antwerp, Belgium funded by an Alfa project of the European Union. Research field: Development of ion selective electrodes (ISE) based on PVC membranes with ionophores to be used in Argentina as potentiometric sensors. Advisor: Prof. Dr. Luc Nagels.
  • 2004: Three months stance at the Biophysical Institute of Palermo, CNR, Italy. Research field: Rheological studies on pectin gels. Advisor: Dr. Donatella Bulone.
  • 04/2004-03/2008: Postgraduate Fellowship of CONICET. Research field: “Encapsulation of volatile compounds in gels and analysis of their release with electronic noses. Preparation and rheological characterization of gels”. Place of work: INQUIMAE, DQIAQF, UBA, Argentina. Advisor: Prof. Martín Negri.
  • 2002: Visiting graduate student at the University of Antwerp, Belgium. Research field: Development of potentiometric sensors. Travel grant from the of the Argentine National Agency of Scientific and Technological Promotion (ANPCyT). Advisor: Prof. Dr. Luc Nagels.
  • 05/2002-04/2003: Postgraduate Fellowship of ANPCyT. Research field: “Electronic noses for the study of flavours released from microheterogeneous means”. Place of work: INQUIMAE, DQIAQF, UBA, Argentina. Advisor: Dr. Martín Negri.
  • 04/2000-09/2001: Undergraduate UBA Scholarship. Research field: "Study of the photochemical behaviour of organic substances naturally or artificially exposed to UV radiation – organic photochemistry – environmental photochemistry. Analytical applications of the organic photochemistry". Department of Organic Chemistry. School of Sciences, UBA, Argentina. Advisor: Dr. Rosa Erra-Balsells.

 
HONORS, AWARDS, AND RECOGNITIONS

  • 2026: Chair, 22nd Annual Conference of the Metabolomics Society (Metabolomics 2026)
  • 2025: Executive Editor of Metabolomics (Springer Nature)
  • 2024: Secretary of the Metabolomics Society
  • 2024: President of the Argentine Mass Spectrometry Society
  • 2024: President of the V Argentine Mass Spectrometry Conference
  • 2024: Journal cover of the Special Issue “Celebrating Women in Proteomics and Metabolomics” in the Journal of Proteome Research https://pubs.acs.org/toc/jprobs/23/8.
  • 2024: Invited participant of the Dagstuhl Seminar 24181 Computational Metabolomics: Towards Molecules, Models, and their Meaning (Apr 28 – May 03, 2024) https://www.dagstuhl.de/en/seminars/seminar-calendar/seminar-details/24181
  • 2023: Invited by the Education and Training Committee of the Metabolomics Society to participate as a panelist in the Podcast webinar series “Educating the Researcher: Traceable Sample Management & Processing” https://metabolomicssociety.org/resources/multimedia-2/education-and-training-committee-webinars/. April 23, 2023.
  • 2023: Journal cover in Metabolomics: G. Riquelme et al. https://doi.org/10.1007/s11306-023-01976-1.
  • 2022: Vice-President of the Argentine Mass Spectrometry Society
  • 2022: Best Poster award in Basic Research to the work entitled “Reversión Metabólica postquirúrgica en pacientes con carcinoma cellular renal de células claras”, M. Manzi, N. Zabalegui, M.E. Monge, XXV Jornadas Multidisciplinarias de Oncología, October 13-14, 2022, Buenos Aires, Argentina.
  • 2022: Awarded Poster entitled “Deasorrollo y validación de un método por LC-APCI-MS/MS para la cuantificación simultánea de 8 esteroides séricos de relevancia en endocrinología pediátrica”, M.R. Martinefski, V. Ambao, M.E. Rodriguez, M.G. Ballerini, R. Rey, M.E. Monge, M. G. Ropelato, IV Argentine Mass Spectrometry Conference, San Luis, Argentina, October 26-28, 2022.
  • 2022: Elected member of the Board of Directors of the Metabolomics Society since October 2022 for a 2-year period.
  • 2022: “The Metabolomics Society Medal” as a recognition from the Board of Directors of the Metabolomics Society of the Metabolomics Society as a recognition of excellence in the career.
  • 2022: “Females in Mass Spectrometry Empowerment Award” as a recognition of dedication to mass spectrometry research and applications.
  • 2022: Invited participant of the Dagstuhl Seminar entitled “Computational Metabolomics: from spectra to knowledge”, Dagsthul, Germany, 1-6 May 2022. https://www.dagstuhl.de/en/program/calendar/semhp/?semnr=22181
  • 2021: Publications selected for the virtual issue of the American Chemical Society (https://doi.org/10.1021/acs.analchem.8b04259, https://doi.org/10.1021/acs.jproteome.8b00538) authored by Latin American researchers from 2018 to 2021, and entitled “Scents and Flavors of Mass Spectrometry in Latin America” (https://pubs.acs.org/page/vi/mass-spectrometry-latin-america).
  • 2019: Awarded Poster entitled “Estudio metabolómico no dirigido para el análisis de la influencia de RSUME en los perfiles metabólicos de tumores von Hippel-Lindaudependientes”, M.R. Martinefski, M.E. Knotta, J.M. Gurevich Messina, L. Tedesco, B. Elguero, D. Golniski, C. Pollak, E. Arzt, M.E. Monge, 10th Argentine Analytical Chemistry Conference, Santa Rosa, La Pampa, September 17-20, 2019. Poster award in the Analytical Chemistry Applications Section of the Conference.
  • 2019: Best Flash‐Poster presentation to the work entitled Mass Spectrometry-based non-targeted lipidomics study for biomarker discovery in clear cell renal cell carcinoma, M. Manzi, M. Palazzo, M. E. Knott, N. Zabalegui, P. Beauseroy, P. Yankilevich, M. I. Giménez, M. E. Monge, 4th International Mass Spectrometry School, Sitges, Spain, September 15‐20, 2019.
  • 2018: Accésit 2 Poster Award for Basic Research to the work entitled “Tecnología metabolómica aplicada al estudio de la interacción de RSUME con la proteína von Hippel-Lindau en un modelo in vitro de células de Carcinoma Renal humanas”, J. M. Gurevich Messina, M. E. Knott, L. Tedesco, B. Elguero, C. Pollak, E. Arzt, M. E. Monge. XXXIII Jornadas Multidisciplinarias del Instituto de Oncología Ángel H. Roffo, Ciudad de Buenos Aires, 3-4 de octubre de 2018.
  • 2016: ACS Pittcon Travel Grant to attend the 2017 Pittsburg Conference on Analytical Chemistry & Applied Spectroscopy (Pittcon), Chicago, Illinois, USA, March 5-9, 2017. American Chemical Society (ACS) Committee on International Activities and ACS Office of International Activities.
  • 2014: Journal cover in The Analyst: R. V. Bennett et al. DOI: 10.1039/c4an00277f.
  • 2013: Journal cover in Chemical Reviews: M.E. Monge et al. DOI: 10.1021/cr300309q.
  • 2013: Awarded Poster entitled “Metabolomics of Disease Progression in an Ovarian Cancer Dicer-Pten Double Knockout Mouse Model.” C. M. Jones, M. E. Monge, J. Kim, M. M. Matzuk, F. M. Fernández. Georgia Tech Research and Innovation Conference, Atlanta, USA, February 2nd, 2013.
  • 2012: Feature article in Proceedings of the National Academy of Sciences of the United States of America: M. E. Monge et al. DOI: 10.1073/pnas.1120593109.
  • 2009: ACCENT-Goldschmidt Young Scientist Travel Award (ACCENT Aerosols Joint Research Programme) to attend the Goldschmidt Conference 2009: Challenges to Our Volatile Planet, Davos, Switzerland.
  • 2007: Best Poster in the section “Pysical chemistry applied to the analysis and technology” entitled “Desarrollo de sensores potenciométricos para la detección de iones metálicos en agua”. María Eugenia Monge, Yamili Toum, Luc Nagels, Estela Andrade and R. Martín Negri; XV Congreso Argentino de Fisicoquímica y Química Inorgánica, Tandil, Buenos Aires, Argentina, April 17-20 2007.
  • 2004: Journal cover in Combinatorial Chemistry & High Throughput Screening: M E Monge et al. DOI : 10.2174/1386207043328689
  • 2002: European Union Travel Grant to attend 5th Green Chemistry Summer School, Universidad Ca’ Foscari, Venice, Italy.

 
 BIOSKETCH  

  • Born on May 5th 1978 in Buenos Aires, Argentina.
  • 2001 Chemistry Degree (Licenciada en Ciencias Químicas), School of Science (FCEN), University of Buenos Aires (UBA).
  • 2006 PhD in Chemistry. Inorganic, Analytical and Physical Chemistry Department, UBA. Advisor: Prof. R. Martín Negri.
  • 2007 Postdoctoral stance at Instituto de Biofísica de Palermo in the research group of Dr. Pier Luigi San Biagio, Consiglio Nazionale delle Ricerche (CNR), Italy.
  • 2008-2011 Postdoctoral Research Fellow at IRCELYON in the research group of Dr. Christian George, Centre National de la Recherche Scientifique (CNRS), Lyon, France.
  • 2012-2013 Researche Scientist I at Georgia Institute of Technology in the research group of Prof. Facundo M. Fernández, Atlanta, USA.
  • 2014-Present. Head of the Mass Spectrometry Group at CIBION
  • 2015-Present  Scientific Officer of the  Mass Spectrometry  Facility at CIBION
  • 2019. Guest editor of the Journal Metabolites for the Special Issue "Mass Spectrometry-Based Metabolomics: Challenges and Applications". www.mdpi.com/journal/metabolites/special_issues/MS_Metabolomics_Challenges#editors
  • 2019-Present  Member of the metabolomics Quality Assurance & Quality Control Consortium (mQACC).
  • 06/2019-07/2019:  Visiting Researcher at the research group of Dr. Christian George at IRCELYON-CNRS, France, in the frame of a MSCA-RISE Horizon2020 research project (no. 690958).
  • 2020  Editorial Board Member  of    GigaByte
  • Member of the Latin American Metabolic Profiling Society (LAMPS, https://jwist.github.io/lamps/index.html)

 
SCIENCE COMMUNICATION

 
COURSES FOR GRADUATE STUDENTS AND POSTDOCS

International metabolomics  course CABBIO 2019 in CIBION.
Advance metabolomics course: Estudios metabolómicos no dirigidos (untargeted) empleando espectrometría de masas y resonancia magnética nuclear como plataformas analíticas.
International course CABBIO 2017
Invited Lecturer at I MetCore Metabolomics School  “Fundamentals and applications of mass spectrometry-based metabolomics”, Universidad de los Andes, Bogotá,  Colombia. 2019.

 

PUBLICATIONS
Full list of publications