Bioanalytical Mass Spectrometry    ->   Publications by María Eugenia Monge, Ph.D.

C. Umansky, A. E. Morellato, M. Rieckher, M. A. Scheidegger, M. R. Martinefski, G. A. Fernández, O. Pak, K. Kolesnikova, H. Reingruber, M. Bollini, G. P. Crossan, N. Sommer, M. E. Monge, B. Schumacher and L. B. Pontel, “Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity” Nature Communications (2022) 13:745. DOI: 10.1038/s41467-022-28242-7.

S. Tomaz, D. Wang, N. Zabalegui, D. Li, H. Lamkaddam, F. Bachmeier, A. Vogel, M. E. Monge, S. Perrier1, U. Baltensperger, C. George, M. Rissanen, M. Ehn, I. El Haddad, M. Riva, “Structures and reactivity of peroxy radicals and dimeric products revealed by online tandem mass spectrometry”Nature Communications (2021) 12:300 DOI:10.1038/s41467-020-20532-2.

Malena Manzi, Martín Palazzo, María Elena Knott, Pierre Beauseroy, Patricio Yankilevich, María Isabel Giménez, and María Eugenia Monge, "Coupled Mass-Spectrometry-Based Lipidomics Machine Learning Approach for Early Detection of Clear Cell Renal Cell Carcinoma", Journal of Proteome Research  2021:20 (1) 841-857. DOI: 0.1021/acs.jproteome.0c00663.  https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00663

M.R. Martinefski, B. Elguero, M. E. Knott, D. Gonilski, L. Tedesco, J. M. Gurevich Messina, C. Pollak, E. Arzt, and M. E. Monge* “Mass Spectrometry-based Metabolic Fingerprinting Contributes to Unveil the Role of RSUME in Renal Cell Carcinoma Cell Metabolism”Journal of Proteome Research 2021;20 (1) : 786-803  DOI: 10.1021/acs.jproteome.0c00655

G. Riquelme,  N. Zabalegui, P. Marchi, C. M. Jones y  M. E. Monge*
“A Python-Based Pipeline for Preprocessing LC-MS Data for Untargeted Metabolomics Workflows”
En   Metabolites, 10 (2020) 416.  DOI: 10.3390/metabo10100416

A. M.  Evans, C. O’Donovan, M. Playdon, C. Beecher, R. D. Beger, J. A. Bowden, D. Broadhurs, C. B. Clish , S. Dasari, W.B. Dunn, J. L. Griffin, T. Hartung, P.‑ C. Hsu, T. Huan, J. Jans,  C. M. Jones, M. Kachman, A. Kleensang, M. R. Lewis, M. E. Monge, J. D. Mosley, E. Taylor, F. Tayyari, G. Theodoridis, F. Torta, B.K. Ubhi,  D. Vuckovic,   behalf of the Metabolomics Quality Assurance, Quality Control Consortium (mQACC),
“Dissemination and análisis of the quality assurance (QA) and quality control (QC) practices of LC-MS based untargeted metabolomics practitioners.”
Metabolomics 16 ( 2020); 113. DOI: 10.1007/s11306-020-01728-5

N. Zabalegui, M. Manzi, A. Depoorter, N. Hayeck, M. Roveretto, C. Li, M. van Pinxteren, H. Herrmann, C. George, and M. E. Monge *, “Seawater Analysis by Ambient Mass Spectrometry-Based Seaomics”

Atmospheric Chemistry and Physics 20(2020) 6243–6257 DOI: 10.5194/acp-20-6243-2020

M. van Pinxteren, K. Wadinga Fomba, N. Triesch, C. Stolle, O. Wurl, E. Bahlmann, X. Gong, J. Voigtländer, H. Wex, T.-B. Robinson, S. Barthel, S. Zeppenfeld, E. H. Hoffmann, M. Roveretto, C. Li, B. Grosselin, V. Daële, F. Senf, D. van Pinxteren, M. Manzi, N. Zabalegui, S. Frka, B. Gašparović, R. Pereira, T. Li, L. Wen, J. Li, C. Zhu, H. Chen, J. Chen, B. Fiedler, W. von Tümpling, K. A. Read, S. Punjabi, A. C. C. Lewis, J. R. Hopkins, L. J. Carpenter, I. Peeken, T. Rixen, D. Schulz-Bull, M. E. Monge, A. Mellouki, C. George, F. Stratmann, and H. Herrmann,  “Marine organic matter in the remote environment of the Cape Verde Islands – An introduction and overview to the MarParCloud campaign”

Atmospheric Chemistry and Physics 20(2020) 6921–6951 DOI: 10.5194/acp-20-6921-2020

A. Seleem, N. Rodrigues de Almeida, Y. Singh Chhonker, D. J. Murry, Z. da Rosa Guterres, A. M. Blocker, S. Kuwabara, D. J. Fisher, E. S. Leal, M. R. Martinefski, M. Bollini, M. E. Monge, S. P. Ouellette, M. Conda-Sheridan, “Synthesis and Antichlamydial Activity of Molecules Based on Dysregulators of Cylindrical Proteases”
Journal of Medicinal Chemistry 63(2020)4370-4387

Manzi, G. Riquelme, N. Zabalegui and M. E. Monge *, “Improving Diagnosis of Genitourinary Cancers: Biomarker Discovery Strategies through Mass Spectrometry-based Metabolomics” 
Journal of Pharmaceutical and Biomedical Analysis 178(2020) 112905

Xiaoling Zang, Maria Eugenia Monge, David A. Gaul, Nael A. McCarty, Arlene Stecenko, Facundo M Fernandez
“Early Detection of Cystic Fibrosis Acute Pulmonary Exacerbations by Exhaled Breath Condensate Metabolomics”
Journal of Proteome Research 19 (2020)144-152

Malena Manzi, Gabriel Riquelme, Nicolás Zabalegui, María Eugenia Monge
“Improving Diagnosis of Genitourinary Cancers: Biomarker Discovery Strategies through Mass Spectrometry-based Metabolomics”
Journal of Pharmaceutical and Biomedical Analysis 178 (2019) article 112905

Emilse Leal, Natalia Adler, Gabriela Fernández, Leopoldo Gebhard, Leandro Battini, Maria Aucar, Mariela Videla, María Eugenia Monge, Alejandro Hernández de los Ríos, John Acosta Dávila, María Morell, Sandra Cordo, Cybele García, Andrea Gamarnik, Claudio Cavasotto, Mariela, Bollini
"De novo design approaches targeting an envelope protein pocket to identify small molecules against dengue virus"
European Journal of Medicinal Chemistry 182 (2019) article 111628

X. Zang, M. E. Monge*, F.M. Fernández*
“Mass Spectrometry-Based Non-targeted Metabolic Profiling for Disease Detection: Recent Developments”
Trends in Analytical Chemistry 118 (2019) 158-169

M. E. Monge, J. N. Dodds, E. S. Baker, A. S. Edison, F. M. Fernández
“Challenges in Identifying the Dark Molecules of Life”
Annual Review of Analytical Chemistry 12 (2019) 177-199

Chaevien S. Clendinen, David A. Gaul, Maria Eugenia Monge, Rebecca S Arnold, Arthur S Edison, John A Petros, and Facundo M Fernandez
"Preoperative Metabolic Signatures of Prostate Cancer Recurrence Following Radical Prostatectomy"
Journal of Proteome Research 18 (2019) 1316–1327. DOI: 10.1021/acs.jproteome.8b00926

X. Zang, M. E. Monge, D. A. Gaul, and F. M. Fernández
"Flow Injection-Traveling Wave Ion Mobility-Mass Spectrometry for Rapid Prostate Cancer Metabolomics"
Analytical Chemistry 90 (2018) 13767-13774. DOI: 10.1021/acs.analchem.8b04259

María Elena Knott, Malena Manzi, Nicolás Zabalegui, Mario O. Salazar, Lydia I. Puricelli, and María Eugenia Monge*
“Metabolic Footprinting of a Clear Cell Renal Cell Carcinoma in vitro Model for Human Kidney Cancer Detection”
Journal of Proteome Research 17 (2018) 3877–3888. DOI: 10.1021/acs.jproteome.8b00538

Daniela M. Fidalgo, Maria Eugenia Monge, Oscar Varela, Adriana Kolender
"Synthesis, Secondary Structure and Anion Binding of Acyclic Carbohydrate‐derived Oligo(amide‐triazole)s"
European Journal of Organic Chemistry 2018 (2018) 6787–6799. DOI: 10.1002/ejoc.201801320

C. S. Clendinen, M. E. Monge*, F. M. Fernandez*
"Ambient Mass Spectrometry in Metabolomics"
Analyst 142 (2017) 3101-3117 DOI: 10.1039/C7AN00700K

X. Zang, J. J. Pérez, C. M. Jones, M. E. Monge, N. A. McCarty, A. A. Stecenko, F. M. Fernández
"Comparison of Ambient and Atmospheric Pressure Ion Sources for Cystic Fibrosis Exhaled Breath Condensate Ion Mobility-Mass Spectrometry Metabolomics"
Journal of The American Society for Mass Spectrometry 28 (2017) 1489-1496 DOI: 10.1007/s13361-017-1660-9

X. Zang, M. E. Monge, N. A. McCarty, A. A. Stecenko, F. M. Fernández
“Feasibility of Early Detection of Cystic Fibrosis Acute Pulmonary Exacerbations by Exhaled Breath Condensate Metabolomics: A Pilot Study”
Journal of Proteome Research 16 (2016) 550-558 DOI: 10.1021/acs.jproteome.6b00675

C. Jones, M. E. Monge, J. Kim, M. M. Matzuk, F. M. Fernández.
“Metabolomic Serum Profiling Detects Early-Stage High-Grade Serous Ovarian Cancer in a Mouse Model”
Journal of Proteome Research 14 (2015) 917-927.

P. N. Newton, P. Tabernero, P. Dwivedi, M. J. Culzoni, M. E. Monge, I. Swamidoss, D. Mildenhall, M. D. Green, R. Jähnke, M. dos Santos de Oliveira, J. Simao, N. J White, F. M. Fernández
“Falsified medicines in Africa and public health – ‘No Action–Talk Only’”
The Lancet Global Health 2 (2014) e509-e510.

A. Kaylor, P. Dwivedi, J. J. Pittman, M. E. Monge, G. Cheng, S. Li, F. M. Fernández
“Plasma-Spray Ionization (PLASI): A Multimodal Atmospheric Pressure Ion Source for Liquid Stream Analysis”
Journal of The American Society for Mass Spectrometry 25 (2014) 1788-1793.

X. Zang, C. M. Jones, T. Q. Long, M. E. Monge, M. Zhou, L. D. Walker, R. Mezencev, A. Gray, J. F. McDonald, and F. M. Fernández
“Feasibility of Detecting Prostate Cancer by Ultraperformance Liquid Chromatography−Mass Spectrometry Serum Metabolomics”
Journal of Proteome Research 13 (2014) 3444-3454

M. E. Monge, P. Dwivedi, M. Zhou, M. Payne, C. Harris, B. House, y. Juggins, P. Cizmarik, P. N. Newton, F. M. Fernández, D. Jenkins.
“A tiered analytical approach for investigating poor quality emergency contraceptives.”
PLoS ONE 9 (4) (2014) e95353

R. V. Bennett, E. M. Morzan, J. O. Huckaby, M. E. Monge, H. I. Christensen, F. M. Fernández
“Robotic Plasma Probe Ionization Mass Spectrometry (RoPPI-MS) of Non-PlanarSurfaces”
Analyst 139 (2014) 2658-2662

M. E. Monge, J. J. Pérez, P. Dwivedi, M. Zhou, N. A. McCarty, A. A. Stecenko, F. M. Fernández
“Ion Mobility and Liquid Chromatography-Mass Spectrometry Strategies for Exhaled Breath Condensate Glucose Quantitation in Cystic Fibrosis Studies”
Rapid Communications in Mass Spectrometry 27 (2013) 2263-2271

M. E. Monge, G.A. Harris, P. Dwivedi, F. M. Fernández.
“Mass Spectrometry-Recent Advances in Direct Open Air Surface Sampling/Ionization”
Chemical Reviews 113 (2013) 2269-2308

M. E. Monge, T. Rosenørn, O. Favez, M. Müller, G. Adler, A. A.Riziq, Y. Rudich, C. George, B. D’Anna.
“Alternative pathway for atmospheric particles growth”
Proceedings of the National Academy of Sciences 109 (2012) 6840-6844 Artículo destacado en PNAS.

M. Amenta, M. E. Monge, L. Lizarraga, D. Giacomazza, V. Guarrasi, P. L. San Biagio, D. Bulone.
“Multivariate Data Analysis of Thermally Treated Sicilian Extravirgin Olive Oils. Coupling of Electronic Nose, Gas Chromatography-mass Spectrometry and Rheology Techniques”
The Open Food Science Journal 6 (2012) 24-32

V. Zelenay, M. E. Monge, B. D'Anna, C. George, S.A. Styler, T. Huthwelker, M. Ammann.
“Increased steady state uptake of ozone on soot due to UV/Vis radiation”
Journal of Geophysical Research – Atmospheres 116 (2011) D11301

C. Baduel, M.E. Monge, D. Voisin, J.L. Jaffrezo, C. George, I. El Haddad, N. Marchand, B. D'Anna.
“Oxidation of Atmospheric Humic Like Substances by Ozone: A Kinetic and Structural Analysis Approach”
Environmental Science & Technology 45 (2011) 5238-5244

R. Ammar, M.E. Monge, C. George, B. D’Anna.
“Photoenhanced NO2 loss on simulated urban grime”
ChemPhysChem 11 (2010) 3956-3961

M.E. Monge, C. George, B. D'Anna, J.F. Doussin, A. Jammoul, J. Wang, G. Eyglunent, G. Solignac, V. Daele, A. Mellouki.
“Ozone Formation from Illuminated Titanium Dioxide Surfaces”
Journal of the American Chemical Society 132 (2010) 8234-8235

M.E. Monge, B. D'Anna and C. George.
“Nitrogen dioxide removal and nitrous acid formation on titanium oxide surfaces—an air quality remediation process?”
Physical Chemistry Chemical Physics 12 (2010) 8991-8998

M.E. Monge, B. D’Anna, L. Mazri, A. Giroir-Fendler, M. Ammann, D.J. Donaldson, and C. George
“Light changes the atmospheric reactivity of soot”
Proceedings of the National Academy of Sciences 107 (2010) 6605-6609

S.D. Rodriguez, M.E. Monge, A.C. Olivieri, R.M. Negri and D.L. Bernik
“Time dependence of the aroma pattern emitted by an encapsulated essence studied by means of electronic noses and chemometric analysis”
Food Research International 43 (2010) 797-804

M.E. Monge, R.M. Negri, D. Giacomazza and D. Bulone
“Correlation between Rheological properties and limonene release in pectin gels using an electronic nose”
Food Hydrocolloids 22 (2008) 916-924

M.E. Monge, R.M. Negri, A.A. Kolenderand R. Erra-Balsells.
“Structural characterization of native high-methoxylated pectin using NMR spectroscopy and UV-Maldi-TOF mass spectrometry. Comparative use of 2,5-dihydroxybenzoic acid and nor-harmane as UV-Maldi matrices”
Rapid Communications in Mass Spectrometry 21 (2007) 2638-2646

L.J. Nagels, J. Everaert, B. Vissers, J. Sekula, H. Bohets, M. Monge, K. Peeters, N. Vervoort, K. Sadowska, D. Koziowska, M. Brewster, K. Vanhoutte.
“Molecular interaction sensors: A new type of detector for separation methods”
LC-GC Europe 20 (2007) 558-566

D. L. Bernik, D. Zubiri, M.E. Monge and R.M. Negri.
“New kinetic model of drug release from swollen gels under non-sink conditions.”
Colloids and Surfaces A: Physicochemical and Engineering Aspects 273 (2006) 165-173

M. E. Monge, D. Bulone, D. Giacomazza, R.M. Negri and D.L. Bernik.
“Electronic Nose screening of limonene release from multicomponent essential oils encapsulated in pectin gels.”
Combinatorial Chemistry & High Throughput Screening 7 (2004) 337-344

M.E. Monge, D. Bulone, D. Giacomazza, D.L. Bernik and R. Martín Negri.
“Detection of Flavor Release from Pectin Gels using Electronic Noses.”
Sensors & Actuators B 101 (2004) 28-38

G. Bazylak, L.J. Nagels, M.E. Monge.
“Macrocycle versus podant-type neutral ionophore in potentiometric detection of mucolytic agents following separation by various HPLC modes.”
Chromatographia 57 (2003) 757-765

M.E. Monge, S.M. Bonesi and R. Erra-Balsells.
“Synthesis and isolation of iodocarbazoles. Direct iodination reaction of N-substituted carbazoles.”
Journal of Heterocyclic Chemistry 39 (2002) 933-941

Proceedings

M.E. Monge, B. D’Anna, C. George.
“Photoenhanced uptake of NO2 on soot.”Geochimica et Cosmochimica Acta 19th Annual VM Goldschmidt Conference, Davos, Suiza, 21-26 de junio de 2009.

M.E. Monge, L. Nagels, E.M. Andrade and R.M. Negri.
“A novel design of potentiometric sensors for metal ions detection.” 2nd international conference on the Electrochemical Promotion of Catalysis and its Applications (EPOCAP) on the, Isla de Oléron, Francia, 29 de Septiembre– 3 de Octubre de 2008

M. Langenheim, M. Lovino, M.E. Monge, D. Mizrahi, R.M. Negri.
“Trends Towards An Electronic Nose-Electronic Tongue Fusion Applied to Discrimination of Wines.” 1º Workshop: "Interdisciplinary aspects of Human-Machine Co-existence and Co-operation". Czech-Argentine Biennale Workshop "e – Golems”, Praga, República Checa, 3-5 de Julio de 2005.
Book Chapters

María Eugenia Monge and Facundo M. Fernández
"An Introduction to Ambient Ionization Mass Spectrometry"
En Ambient Ionization Mass Spectrometry. Editors: Marek A. Domin and Robert B. Cody, The Royal Society of Chemistry, RSC Publishing, Cambridge, 2014. ISBN: 978-1-84973-926-9.

Christina Jones, María Eugenia Monge, Facundo M. Fernández.
"Metabolite Profiling by Direct Analysis in Real Time Mass Spectrometry"
En Mass Spectrometry Methods in Metabolomics: Methods and Protocols Series Methods in Molecular Biology, Vol.1198, Editor: Daniel Raftery, Humana Press USA, Springer publishing group, NY, 2014. ISBN 978-1-4939-1258-2.

Patents
“Mass Spectrometry metabolic profiles as a diagnostic for prostate cancer”, provisional patent submitted 05/23/2014. GTRC ID 6138. USPTO serial number 62/002,728. Inventors: Facundo M. Fernández, John McDonald, Alex Gray, Christina Jones, Xiaoling Zang, María Eugenia Monge